Bioimpressão no Transplante de Órgãos: Dos Modelos Experimentais às Perspectivas Clínicas
Palabras clave:
Tissue Engineering, 3D Printing Technologies, Graft Viability, Biomedical Innovation, Implantable ConstructsResumen
Introdução: A bioimpressão despontou como uma tecnologia inovadora no transplante de órgãos e na medicina regenerativa, visando solucionar desafios urgentes, como a escassez de órgãos de doadores e a necessidade de reparo eficaz de tecidos. Ao aproveitar as técnicas avançadas de impressão 3D, a bioimpressão permite a fabricação de tecidos e órgãos funcionais com propriedades arquitetônicas e biológicas precisas. Métodos: Esta revisão fornece uma análise detalhada dos últimos avanços em bioimpressão, concentrando-se em técnicas de ponta, no desenvolvimento de biotintas e em suas aplicações na engenharia de tecidos. Ela examina os avanços significativos na criação de protótipos de órgãos vascularizados e transplantáveis e explora a função da bioimpressão na medicina personalizada. Resultados: As descobertas destacam o impacto transformador da bioimpressão no campo biomédico, particularmente em testes de medicamentos, modelagem terapêutica e estratégias de tratamento específicas para o paciente. Além disso, os principais desafios — incluindo limitações tecnológicas, preocupações éticas e considerações regulatórias — são discutidos para fornecer uma compreensão abrangente do progresso do campo e dos possíveis obstáculos. Conclusão: A bioimpressão é imensamente promissora para revolucionar a saúde global, oferecendo soluções para a escassez de órgãos e o avanço da medicina regenerativa. No entanto a pesquisa e a inovação contínuas são necessárias para superar os desafios existentes e facilitar sua tradução clínica para a prática médica convencional.
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Esta obra está bajo una licencia internacional Creative Commons Atribución 4.0.
