Comparison of Clinical and Functional Outcomes Patients with Use of Extracorporeal Membrane Oxygenation During the Perioperative of Lung Transplantation

Authors

  • Iuri Dalla Vecchia Hospital de Clínicas de Porto Alegre – Programa de Residência Integrada Multiprofissional em Saúde Clínica Cirúrgica – Porto Alegre (RS) – Brazil. https://orcid.org/0009-0005-6427-5681
  • Mariana Zirkel Andriotti Universidade Federal do Rio Grande do Sul – Escola de Educação Física, Fisioterapia e Dança – Porto Alegre (RS) – Brazil. https://orcid.org/0009-0004-6826-5942
  • Gracieli Nadalon Deponti Hospital de Clínicas de Porto Alegre – Serviço de Fisioterapia – Porto Alegre (RS) – Brazil. https://orcid.org/0000-0001-5896-6703
  • Fábio Cangeri Di Naso Hospital de Clínicas de Porto Alegre – Programa de Residência Integrada Multiprofissional em Saúde Clínica Cirúrgica – Porto Alegre (RS) – Brazil | Universidade Federal do Rio Grande do Sul – Escola de Educação Física, Fisioterapia e Dança – Porto Alegre (RS) – Brazil. https://orcid.org/0000-0002-5306-5743

Keywords:

Lung Transplantation, Extracorporeal Membrane Oxygenation, Physical Therapy Modalities, Rehabilitation, Early Mobilization, Intensive Care Unit

Abstract

Objectives:  To compare clinical and functional outcomes between lung transplant patients who used intra and/or postoperative extracorporeal membrane oxygenation (ECMO) and those who did not. Methods:  Retrospective cohort study. Pre- and post-lung transplant data from 2009 to September 2023 were collected. Clinical outcomes considered were duration of invasive mechanical ventilation (IMV), length of stay in the intensive care unit (ICU) and hospital, and in-hospital mortality. Functional outcomes included time to achieve sitting at the bedside and initiate walking, patient’s mobility at ICU discharge measured by the ICU Mobility Scale (IMS), and differences in functional performance measured by the 6-minute walk test (6MWT). Results:  A total of 73 transplants were performed, with 43.8% utilizing ECMO. There was no difference in time on IMV, ICU, and hospital length of stay. In-hospital mortality was 43.8% (ECMO group) and 17.1% (non-ECMO group) (p = 0.019). The ECMO group took longer to achieve bedside sitting and initiate walking (median of 5 and 7 days, respectively) compared to the non-ECMO group (median of 2 and 3 days, respectively) (p 0.001 and p = 0.004). However, there was no difference in patients’ mobility at ICU discharge and the predicted 6MWT performance post-hospital discharge. Conclusion:  Despite the association of ECMO use with clinical and structural barriers to mobilizing critical patients, functional rehabilitation was feasible and comparable to patients who did not use ECMO.

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Published

2025-06-09

How to Cite

1.
Vecchia ID, Andriotti MZ, Deponti GN, Naso FCD. Comparison of Clinical and Functional Outcomes Patients with Use of Extracorporeal Membrane Oxygenation During the Perioperative of Lung Transplantation. bjt [Internet]. 2025 Jun. 9 [cited 2025 Jun. 18];28. Available from: https://bjt.emnuvens.com.br/revista/article/view/685

Issue

Vol. 28 (2025)

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Original Paper

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Copyright (c) 2025 Iuri Dalla Vecchia, Mariana Zirkel Andriotti, Gracieli Nadalon Deponti, Fábio Cangeri Di Naso

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