Extracorporeal Membrane Oxygenation use on Liver Transplantation: An Integrative Review

Authors

  • Henrique Nóbrega Zoby Universidade de Pernambuco – Faculdade de Ciências Médicas – Departamento de Iniciação à Metodologia de Pesquisa – Recife/PE – Brazil. https://orcid.org/0000-0002-8834-6545
  • Luísa Borges Oliveira de Arruda Falcão Universidade de Pernambuco – Faculdade de Ciências Médicas – Departamento de Iniciação à Metodologia de Pesquisa – Recife/PE – Brazil. https://orcid.org/0000-0003-0759-8992
  • Laura Cabral Barros Correia Universidade de Pernambuco – Faculdade de Ciências Médicas – Departamento de Iniciação à Metodologia de Pesquisa – Recife/PE – Brazil. https://orcid.org/0000-0002-5538-0632
  • Marlon Vinicius Alves Soares Rêgo Universidade de Pernambuco – Faculdade de Ciências Médicas – Departamento de Iniciação à Metodologia de Pesquisa – Recife/PE – Brazil. https://orcid.org/0000-0003-4637-8327
  • Giovanna Vasconcelos Wanderley Universidade de Pernambuco – Faculdade de Ciências Médicas – Departamento de Iniciação à Metodologia de Pesquisa – Recife/PE – Brazil. https://orcid.org/0000-0002-4525-005X
  • Fernando Pires de Góes Vilachan Universidade de Pernambuco – Faculdade de Ciências Médicas – Departamento de Iniciação à Metodologia de Pesquisa – Recife/PE – Brazil. https://orcid.org/0000-0003-4521-2392
  • Carlos Vinicius de Oliveira Lima Universidade de Pernambuco – Faculdade de Ciências Médicas – Departamento de Iniciação à Metodologia de Pesquisa – Recife/PE – Brazil. https://orcid.org/0000-0002-0538-9874
  • Ludmila Rodrigues Oliveira Costa Universidade de Pernambuco – Faculdade de Ciências Médicas – Departamento de Iniciação à Metodologia de Pesquisa – Recife/PE – Brazil. https://orcid.org/0000-0001-7137-4323
  • Hugo Rafael Souza e Silva Universidade de Pernambuco – Faculdade de Ciências Médicas – Departamento de Iniciação à Metodologia de Pesquisa – Recife/PE – Brazil. https://orcid.org/0000-0002-7958-2474
  • Olival Cirilo Lucena da Fonseca Neto Universidade de Pernambuco – Hospital Universitário Oswaldo Cruz – Serviço de Cirurgia Geral e Transplante de Fígado – Recife/PE – Brazil.

Keywords:

Extracorporeal Membrane Oxygenation, ECMO, ECMO Treatment, Liver transplantation, Hepatic transplant, Perioperative period

Abstract

Objective: To review the applicability of extracorporeal membrane oxygenation (ECMO) during the pre, intra and postoperative periods of patients undergoing liver transplantation. Methods: This is an integrative review that seeks to evaluate the indications for the use of ECMO in liver transplantation. As databases, were used: MEDLINE, Web of Science and Scopus, with articles published in the last ten years in English and Portuguese. Results: In this review, 24 papers were included, of which 3 were original articles and 21 were case reports. The studies were divided according to the ECMO application period concerning the liver transplant: one for the preoperative, eight intraoperative and 15 postoperative. It was identified that ECMO use is mainly related to hepatopulmonary syndrome complications. The limited number of studies regarding using ECMO in the preoperative period reflects the importance of hepatic transplant as the main measure to manage liver disease complications. In the intraoperative phase, ECMO usage is expressive in managing cardiopulmonary complications refractory to previous interventions. The use of this mechanism in the postoperative period is the most reported. The main indication is severe hypoxemia secondary to hepatopulmonary syndrome, in which other treatments have been ineffective. The main complications related to this mechanism were sepsis, renal failure and bleeding. Conclusion: ECMO is an important therapeutic modality for managing complications resulting from liver transplantation. However, only some  studies in the literature have an adequate sample number to assess its actual efficacy and level of safety.

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Published

2023-01-26

How to Cite

Zoby, H. N., Falcão, L. B. O. de A., Correia, L. C. B. ., Rêgo, M. V. A. S., Wanderley, G. V., Vilachan, F. P. de G., Lima, C. V. de O., Costa, L. R. O., Silva, H. R. S. e ., & Fonseca Neto, O. C. L. da. (2023). Extracorporeal Membrane Oxygenation use on Liver Transplantation: An Integrative Review. Brazilian Journal of Transplantation, 26. Retrieved from https://bjt.emnuvens.com.br/revista/article/view/490

Issue

Vol. 26 (2023)

Section

Review Article

License

Copyright (c) 2023 Henrique Nóbrega Zoby, Luísa Borges Oliveira de Arruda Falcão, Laura Cabral Barros Correia, Marlon Vinicius Alves Soares Rêgo, Giovanna Vasconcelos Wanderley, Fernando Pires de Góes Vilachan, Carlos Vinicius de Oliveira Lima, Ludmila Rodrigues Oliveira Costa, Hugo Rafael Souza e Silva, Olival Cirilo Lucena da Fonseca Neto

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.