Analysis of the initial results on the live donor kidney transplantation program in the State of Pará

Abstract

Purpose: To assess the initial results of this program, as well as identifying the main risk factors related to the graft loss. Methods: 65 living donor kidney transplantations have been retrospectively assessed as to the graft, patients, and total survival in 1, 3, and 5 years. These served as cut-point for the analysis on the importance of many donor and receptor risk factors for the graft loss. To assess the survival, the Kaplan-Meier method was used. The univariate and multivariate Cox regression models were used for the risk factors. Results: The graft survival and patients in 1, 3, and 5 years have been respectively 98%, 91%, and 83%; 98%, 95%, and 87%. The death with good functional graft occurred in 60% patients. The univariate analysis of the risk factors showed in decreasing importance that the amount of transfusions, positive serology for hepatitis and cytomegalovirus as base disease, kind of immunosuppressant, and extent of the dialysis were significant for the graft loss. The multivariate analysis showed no statistic significance. Conclusions: The initial results of this program revealed to be satisfactory. Death due to reasons that were not transplant-related represented an important cause

to the graft loss. Measures aimed to improve the clinic preoperative assessment and acting on the risk factors must be emphasized, seeking to improve the late results of the live donor kidney transplantations.