Profile of arterial gasometries in potential donors of organ and tissue in Sergipe state

Abstract

The conduction way to maintain the deceased donor is essential to the achievement of the transplantation process, and thus resulting in an increase in the organ and tissue supply. Purpose: To assess the arterial blood gases profile in potential organ and tissue donor patients in the state of Sergipe. Methods: A retrospective cohort study on potential donors of organs and tissues from January 2014 to June 2015 assessed at the Organ Procurement Organization Service (OPO). Variables were age, gender, weight, height, Body Mass Index (BMI); date of admission, inpatient facility, hospital and intubation days, infection, use of antibiotics, arterial blood gases. The association between variables was assessed: differences between proportions were analyzed by using the chi-square and Fisher exact tests, and to the analysis of two independent sampling comparison, the Wilcoxon test was used. The statistical significance adopted was p <0.05. Results: It was analyzed 73 cases of patients which evolved to brain death predominantly young adults with average age of 39.55 from which 47 (64%) were male. The average BM attained was 25.63, and the average hospitalization and intubation days were 6.69 and 4.89, respectively. The majority of patients had infection (55%) and 72% of them was using antibiotics. As to the blood gas parameters assessed, it was attained an average of 0.58 for FIO²; 7.26 for pH; 267.63 mmHg for PaO², 42.06 mmHg for PaCO² and 98% for SatO². There was no statistical significance for major part of the crossing performed, except for PaO² between blood gases versus days of intubation, and blood gas pH and presence or absence of infection. Conclusion: The assessment of the blood gas profile from potential donors concluded that they are better when kept in the ICU, those with no infection, and those with below 25 kg/m² BMI, but there was no statistical difference between blood gases from donor or not patients.