Assessment of the liver transplantation in Hospital Santa Isabel of Blumenau/SC from January, 2009 to May, 2015

Abstract

Purpose: To assess patients submitted to liver transplantation in a unique transplantation center of the Hospital Santa Isabel in Blumenau/SC – Brazil, between January 2009 to May 2015. Methods: It is a study retrospective cohort type, in which the patient must be submitted to liver transplantation in the Santa Isabel Hospital of Blumenau/SC. The study was performed through data collection from the records of patients along their hospital stay for the transplant. It was assessed the epidemiological data (age, gender, city of origin, indication for the liver transplantation), MELD score, pos-transplant complications, causes of death and evolution of the transplant (occurrence of re-transplantation, survival and length of stay in Intensive Care Unit). Results: It was a total of 614 patients with average age of 52.23 years. Male sex was prevalent (74,91%). As to the origin, 77.5% were from the State of Santa Catarina and 22.5% were from other states of the Federation. From the total patients, 55,86% had MELD higher or equal to 18. The main indication for the transplant was cirrhosis due to hepatitis C (25.6%) and hepatocellular carcinoma (18,6%). Most patients (70.4%) stayed between 0 and 5 days in ICU. The main causes of mortality was 35.93%, without considering the retransplantation; and the main causes of death after the procedure along 6 years was general causes (34.93%), having cardiovascular as prevalent cause (91.25%), followed by insufficiency of multiple organs (3.75%), cerebrovascular (3.75%) and renal causes (1.25%); septic shock (16.59%), coagulation disorders (5.24%), primary dysfunction (3.93%), and causes not informed (35.8%). The approximate survival rate in 1 and 5 years was respectively, 67.94% and 60.70%. Conclusion: The study disclosed data similar to the literature, proving that this isan evolving service with many good results.