Transplante Intestinal e Multivisceral no Brasil: Coorte Retrospectiva e Análise Global

Juliana Yuka Washiya; Otávio Rocha Fiuza; Gabrielly Santos Pereira; Marcio Yoshio Gushiken; Rafael Antônio Arruda Pecora; Renata Rocha Batista; Igor Lepski Calil; André Ibrahim David

Authors

Juliana Yuka Washiya Universidade Federal de São Paulo – Escola Paulista de Medicina, Departamento de Cirurgia – São Paulo (SP) – Brazil. https://orcid.org/0000-0001-5908-0031
Otávio Rocha Fiuza Universidade Federal de São Paulo – Escola Paulista de Medicina, Departamento de Cirurgia – São Paulo (SP) – Brazil. https://orcid.org/0000-0001-7420-2762
Gabrielly Santos Pereira Universidade Federal de São Paulo – Escola Paulista de Medicina, Departamento de Cirurgia – São Paulo (SP) – Brazil. https://orcid.org/0000-0002-6866-0246
Marcio Yoshio Gushiken Universidade Federal de São Paulo – Escola Paulista de Medicina, Departamento de Cirurgia – São Paulo (SP) – Brazil. https://orcid.org/0000-0001-7830-6120
Rafael Antônio Arruda Pecora Hospital Israelita Albert Einstein – Programa de Transplante Intestinal e Multivisceral – São Paulo (SP) – Brazil. https://orcid.org/0000-0002-5820-0828
Renata Rocha Batista Hospital Israelita Albert Einstein – Programa de Transplante Intestinal e Multivisceral – São Paulo (SP) – Brazil. https://orcid.org/0000-0002-8064-4847
Igor Lepski Calil Hospital Israelita Albert Einstein – Programa de Transplante Intestinal e Multivisceral – São Paulo (SP) – Brazil. https://orcid.org/0000-0002-7734-5491
André Ibrahim David Universidade Federal de São Paulo – Escola Paulista de Medicina, Departamento de Cirurgia – São Paulo (SP) – Brazil. https://orcid.org/0000-0001-9520-5241

Keywords:

Organ transplantation, Survival, Intestinal Failure, Cohort Studies

Abstract

Objectives: To evaluate the clinical characteristics and outcomes of patients undergoing multivisceral transplantation (MVT) in Brazil, comparing the results with major international centers. Waiting time, patient and graft survival, and the postoperative rehabilitation process were analyzed. Methods: Single-center retrospective cohort study. Medical records of nine patients who underwent MVT at a Brazilian tertiary hospital were analyzed. Results: The cohort of nine patients had a median waiting time of 281 days. Patient survival was 66.7% at 1 and 3 years and 53.3% at 5 years post-surgery. No cases of graft rejection were recorded. Postoperative rehabilitation was characterized by a reduction in the duration of total parenteral nutrition, early transition to oral feeding, and multidisciplinary follow-up. Conclusion: Although the sample size is small, the survival rate of patients undergoing MVT in Brazil was comparable to that of international centers (70.64% at 1 year; 57.7% at 3 years; 53.23% at 5 years), despite a significantly longer waiting time (median of 281 days). The postoperative rehabilitation protocol, similar to the global standard, proved to be a beneficial factor in recovery.

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References

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Intestinal and Multivisceral Transplantation in Brazil: A Retrospective Cohort and Global Analysis

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