Collapsing Focal Segmental Glomerulosclerosis in a Kidney Transplant Patient due to Dengue Infection - Case Report

Authors

  • Sammara Azevedo Guedes Universidade Federal da Bahia – Hospital Ana Nery – Salvador (BA) – Brazil | Universidade Federal da Bahia – Hospital Ana Nery – Departamento de Nefrologia e Transplante Renal – Salvador (BA) – Brazil | Escola Bahiana de Medicina e Saúde Pública – Faculdade de Medicina – Salvador (BA) – Brazil. https://orcid.org/0000-0001-8391-8658
  • Gabriel Brayan Gutierrez Peredo Universidade Federal da Bahia – Hospital Ana Nery – Salvador (BA) – Brazil | Universidade Federal da Bahia – Hospital Ana Nery – Departamento de Nefrologia e Transplante Renal – Salvador (BA) – Brazil | Universidade Federal da Bahia – Programa de Pós-Graduação em Medicina e Saúde – Salvador (BA) – Brazil. https://orcid.org/0000-0002-4310-8754
  • Camila Rodrigues Durando Universidade Federal da Bahia – Hospital Ana Nery – Salvador (BA) – Brazil | Universidade Federal da Bahia – Hospital Ana Nery – Departamento de Nefrologia e Transplante Renal – Salvador (BA) – Brazil. https://orcid.org/0009-0004-6451-7137
  • Ítala Silva Mota Universidade Federal da Bahia – Hospital Ana Nery – Salvador (BA) – Brazil | Universidade Federal da Bahia – Hospital Ana Nery – Departamento de Nefrologia e Transplante Renal – Salvador (BA) – Brazil. https://orcid.org/0009-0001-0913-1133
  • Fernanda Pita Mendes da Costa Universidade Federal da Bahia – Hospital Ana Nery – Salvador (BA) – Brazil | Universidade Federal da Bahia – Hospital Ana Nery – Departamento de Nefrologia e Transplante Renal – Salvador (BA) – Brazil. https://orcid.org/0009-0009-9241-2830
  • João Jorge Goes de Codes Universidade Federal da Bahia – Hospital Ana Nery – Salvador (BA) – Brazil | Universidade Federal da Bahia – Hospital Ana Nery – Departamento de Nefrologia e Transplante Renal – Salvador (BA) – Brazil. https://orcid.org/0000-0001-5375-0428
  • Mariana Almeida Maynart Aires Universidade Federal da Bahia – Hospital Ana Nery – Salvador (BA) – Brazil | Universidade Federal da Bahia – Hospital Ana Nery – Departamento de Nefrologia e Transplante Renal – Salvador (BA) – Brazil. https://orcid.org/0009-0004-5792-8819
  • Milena Sampaio Barreto Machado Universidade Federal da Bahia – Hospital Ana Nery – Salvador (BA) – Brazil | Universidade Federal da Bahia – Hospital Ana Nery – Departamento de Nefrologia e Transplante Renal – Salvador (BA) – Brazil. https://orcid.org/0009-0001-7343-6775
  • Nara Alves Vieira Universidade Federal da Bahia – Hospital Ana Nery – Salvador (BA) – Brazil | Universidade Federal da Bahia – Hospital Ana Nery – Departamento de Nefrologia e Transplante Renal – Salvador (BA) – Brazil. https://orcid.org/0009-0008-1891-830X
  • Manuela Lordelo Leite Caldas Pereira Universidade Federal da Bahia – Hospital Ana Nery – Salvador (BA) – Brazil | Universidade Federal da Bahia – Hospital Ana Nery – Departamento de Nefrologia e Transplante Renal – Salvador (BA) – Brazil. https://orcid.org/0009-0008-4340-4300
  • Fernanda Pinheiro Martin Tapioca Universidade Federal da Bahia – Hospital Ana Nery – Salvador (BA) – Brazil | Universidade Federal da Bahia – Hospital Ana Nery – Departamento de Nefrologia e Transplante Renal – Salvador (BA) – Brazil | Universidade Federal da Bahia – Programa de Pós-Graduação em Medicina e Saúde – Salvador (BA) – Brazil. https://orcid.org/0000-0003-2441-9626
  • Ricardo José Costa Mattoso Universidade Federal da Bahia – Hospital Ana Nery – Salvador (BA) – Brazil | Universidade Federal da Bahia – Hospital Ana Nery – Departamento de Nefrologia e Transplante Renal – Salvador (BA) – Brazil | Escola Bahiana de Medicina e Saúde Pública – Faculdade de Medicina – Salvador (BA) – Brazil | Universidade Salvador – Faculdade de Medicina – Salvador (BA) – Brazil. https://orcid.org/0000-0002-3037-8448

Keywords:

Nephrotic Syndrome, Arbovirus, Dengue, Collapsing Focal Segmental Glomerulosclerosis, Kidney Transplant

Abstract

This study reports a case of collapsing focal segmental glomerulosclerosis (FSGS) associated with dengue virus infection in a 20-year-old Afro-descendant patient with a history of kidney transplant due to Alport syndrome. The patient, who had experienced typical dengue symptoms for 3 weeks, developed nephrotic syndrome, worsening renal function, and required renal replacement therapy. Despite treatment with intravenous methylprednisolone, renal function did not improve. A renal biopsy confirmed collapsing FSGS. This case suggests a potential link between dengue and collapsing FSGS in kidney transplant patients, emphasizing the need for vigilance and prompt management in endemic areas.

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References

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Published

2025-03-17

How to Cite

1.
Guedes SA, Peredo GBG, Durando CR, Mota Ítala S, Costa FPM da, Codes JJG de, et al. Collapsing Focal Segmental Glomerulosclerosis in a Kidney Transplant Patient due to Dengue Infection - Case Report. bjt [Internet]. 2025 Mar. 17 [cited 2025 Mar. 30];28. Available from: https://bjt.emnuvens.com.br/revista/article/view/665

Issue

Vol. 28 (2025)

Section

Case Report

License

Copyright (c) 2025 Sammara Azevedo Guedes , Gabriel Brayan Gutierrez Peredo, Camila Rodrigues Durando, Ítala Silva Mota, Fernanda Pita Mendes da Costa, João Jorge Goes de Codes , Mariana Almeida Maynart Aires, Milena Sampaio Barreto Machado, Nara Alves Vieira , Manuela Lordelo Leite Caldas Pereira, Fernanda Pinheiro Martin Tapioca, Ricardo José Costa Mattoso

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This work is licensed under a Creative Commons Attribution 4.0 International License.