Prevalent Complications in Heart Transplantation: A Retrospective Cohort Analysis
Keywords:
Immunosuppression Therapy, Heart Transplantation, Complications Post-Heart Transplantation, NursingAbstract
Objectives: To identify the prevalent complications after heart transplantation. Methods: This is a quantitative retrospectivecohort research with post-h eart transplant patients from 2010 to 2022 through medical record analysis. Results: Forty-nine postheart transplant patients participated in the study, six of whom died. The leading cause of heart failure before transplantation was idiopathic dilated heart failure (36.7%), followed by chagasic etiology (30.6%), with an average transplant waiting time of 7.4 months (standard deviation [SD] = 9.7). In the post-heart transplantation period, 95.9% of the population presented at least one complication, the most common being acute cellular rejection (81.6%), followed by cytomegalovirus infection (44.9%). Conclusion: The study provided relevant data to the literature to identify the prevalent complications in heart transplantation and implement nursing actions such as planning by nurses to improve self-management of care for transplant patients.
Downloads
References
Freitas NCC, Cherchiglia ML, Simão Filho S, Alvares-Teodoro J, Acurcio FA, Guerra Junior AA. Dezesseis anos de transplante cardíaco em coorte aberta no Brasil: análise de sobrevivência de pacientes em uso de imunossupressores. Arq Bras Cardiol 2021;116(4):744-53. https://doi.org/10.36660/abc.20200117
Soares LSS, Brito ES, Silva EV, Galato D. Eventos adversos relacionados ao uso de imunossupressores em pacientes transplantados. Boletim Farmacoterapêutica. 2019 XXIII(3):11-7. Available at: https://crfmt.org.br/wp-content/uploads/2019/11/2628-8937-1-SM.pdf. Acess on Jun 2022.
Moreira MCV, Cunha-Melo JR. Chagas disease infection reactivation after heart transplant. Trop Med Infect Dis. 2020; 5(3):106. https://doi.org/10.3390/tropicalmed5030106
Bacal F, Marcondes-Braga FG, Rohde LEP, Xavier Júnior JL, de Souza Brito F, Moura LZ, et al. 3ª Diretriz Brasileira de Transplante Cardíaco. Arq Bras Cardiol . 2018;111(2). https://doi.org/10.5935/abc.20180153
Potena L, Zuckermann A, Barberini F, Aliabadi-Zuckermann A. Complications of cardiac transplantation. Curr Cardiol Rep. 2018; 20(9):73. https://doi.org/10.1007/s11886-018-1018-3
Lemos BO, Silva RCMA, Silva RF. Prevalence and time of development of systemic arterial hypertension in patients after liver transplantation. Arq Gastroentrol. 2021;58:77-81. https://doi.org/10.1590/S0004-2803.202100000-13
Junta LHJ, Menegat G. Transplante renal e uma nova abordagem: diabetes mellitus pós-transplante renal. Revista da Faculdade de Medicina de Teresópolis. 2018; 2 (1):135-56. Availble at: https://revista.unifeso.edu.br/index.php/faculdadedemedicinadeteresopolis/article/view/714. Acess on Jun 2022.
Bruder RCS. Redução da incidência de citomegalovírus no esquema sirolimo associado à tacrolimo em paciente idoso transplantado renal. Botucatu. Tese [Doutorado em Fisiopatologia em Clínica Médica] – Faculdade de Medicina de Botucatu, Universidade Estadual Paulista “Júlio de Mesquita Filho”; 2018. http://hdl.handle.net/11449/153197
Avila MS, Belfort DSP. Avanço do transplante cardíaco no Brasil: é hora de se construir um banco de dados nacional? Arq Bras Cardiol. 2021;116(4):754-5. https://doi.org/10.36660/abc.20210104
Malta M, Cardoso LO, Bastos FI, Magnanini MMF, Silva CMFP. STROBE initiative: guidelines on reporting observational studies. Rev Saude Publica. 2010; 44(3):559-65. https://doi.org/10.1590/S0034-89102010000300021
Harris PA, Taylor R, Thielke R, Payne J, Gonzalez N, Conde JG. Research electronic data capture (REDCap) – A metadatadriven methodology and workflow process for providing translational research informatics support. J Biomed Inform. 2009;42(2):377-81. https://doi.org/10.1016/j.jbi.2008.08.010
Harris PA, Taylor R, Minor BL, Elliott V, Fernandez M, O’Neal L, et al. The REDCap consortium: building an international community of software partners. J Biomed Inform. 2019; 95:103208. https://doi.org/10.1016/j.jbi.2019.103208
Carvalho WN. Sobrevida de pacientes após o transplante cardíaco e análise da qualidade de vida relacionada à saúde: dados de um centro transplantador brasileiro. Belo Horizonte. Dissertação [Mestrado em Ciências Aplicadas à Saúde do Adulto] –Universidade Federal de Minas Gerais, Faculdade de Medicina; 2019. http://hdl.handle.net/1843/32520
Gonçalves KC. Fatores de risco cardiovascular e doença vascular do enxerto em uma coorte de pacientes submetidos a transplante cardíaco. Belo Horizonte. Dissertação [Mestrado em Ciências Aplicadas à Saúde do Adulto] – Universidade Federal de Minas Gerais, Faculdade de Medicina; 2019. http://hdl.handle.net/1843/BUOS-BCDRXH
Maia Neto VN, Monteiro VS, Carneiro RMD, Guerra EDNP, Vieira GBG, Matos ILP, et al. Perfil clínico e epidemiológico de pacientes com diabetes mellitus pós-transplante cardíaco em um hospital do nordeste do Brasil: estudo de coorte retrospectivo. Recife. Projeto de pesquisa [Programa de Iniciação Científica] – Instituto de Medicina Integral Prof. Fernando Figueira; 2022. http://tcc.fps.edu.br:80/jspui/handle/fpsrepo/1503
Hecking M, Sharif A, Eller K, Jenssen T. Management of post-transplant diabetes: immunosuppression, early prevention, and novel antidiabetics. Transpl Int 2021;34(1):27-48. https://doi.org/10.1111/tri.13783
Ju C, Wang X, Xu X, Xie S, Cao Q, Lin W. Cytomegalovirus seroprevalence, infection, and disease in Chinese thoracic organ transplant recipients: a retrospective cohort study. BMC Infect Dis 2022;22(1):1-7. https://doi.org/10.1186/s12879-022-07853-x
Ge F, Li C, Xu X, Huo Z, Wang R, Wen Y, et al. Cancer risk in heart or lung transplant recipients: a comprehensive analysis of 21 prospective cohorts. Cancer Med 2020;9(24):9595-9610. https://doi.org/10.1002/cam4.3525
Poltronieri NVG, Moreira RSL, Schirmer J, Roza BA. Medication non-adherence in heart transplant patients. Rev Esc Enferm USP 2020;54:e03644. https://doi.org/10.1590/S1980-220X2019009203644
Lohn VL, Flores FLK, Alves BGD. Nursing care for patients undergoing heart transplantation: integrative review. Eur J Health Res 2022;3(1):55-64. https://doi.org/10.54747/ejhrv3n1-004
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Gabriela Ribeiro Borzani, Nadja Van Geen Poltronieri , Sérgio Henrique Simonetti, Bruna Bronhara Damiani
This work is licensed under a Creative Commons Attribution 4.0 International License.
