Transplant in Diffuse Large B-Cell Lymphoma

Authors

  • Guilherme Duffles Universidade Estadual de Campinas – Faculdade de Ciências Médicas – Hematology and Hemotherapy Center, Campinas (SP), Brazil.
  • Carmino De Souza Universidade Estadual de Campinas – Faculdade de Ciências Médicas – Hematology and Hemotherapy Center, Campinas (SP), Brazil.

Keywords:

Lynphoma, Transplantation, Autologous, Transplantation, Allogenic

Abstract

Diffuse large B-cell lymphoma is the most common type of aggressive lymphoma. Patients that don’t respond to first-line therapy have a poor prognosis. Bone marrow transplant represents an effective and established salvage treatment for those patients, with curative potential. Autologous  transplant uses the patient stem cell for rescue after high-dose myeloablative chemotherapy, while allogenic transplant relies on a different stem cell for a graft-versus-lymphoma effect. With distinct toxicity and capacity to induce remission, those therapies have great value in the management of patients with relapsed and refractory diffuse large B-cell lymphoma.

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Published

2022-06-21

How to Cite

1.
Duffles G, De Souza C. Transplant in Diffuse Large B-Cell Lymphoma. bjt [Internet]. 2022 Jun. 21 [cited 2025 Apr. 2];25(2). Available from: https://bjt.emnuvens.com.br/revista/article/view/445

Issue

Vol. 25 No. 2 (2022)

Section

Review Article

License

Copyright (c) 2022 Guilherme Duffles, Carmino De Souza

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.