Atezolizumab plus Bevacizumab as a Bridge for Liver Transplant in Hepatocellular Carcinoma

Authors

  • Gabriela Azevedo Solino Escola Superior de Ciências da Santa Casa de Misericórdia de Vitória – Departamento de Medicina – Vitória/ES – Brasil.
  • Raphael Paiva Cock Ferreira Escola Superior de Ciências da Santa Casa de Misericórdia de Vitória – Departamento de Medicina – Vitória/ES – Brasil.
  • Luiz Augusto Carneiro D’Albuquerque Universidade de São Paulo – Departamento de Transplante Hepático – São Paulo/SP – Brasil.
  • Alberto Queiroz Farias Universidade de São Paulo – Departamento de Transplante Hepático – São Paulo/SP – Brasil.
  • Lívia Zardo Trindade Escola Superior de Ciências da Santa Casa de Misericórdia de Vitória – Departamento de Gastroenterologia e Hepatologia – Vitória/ES – Brasil.
  • Vitor Fiorin de Vasconcelos Universidade Federal do Espírito Santo – Departamento de Oncologia – Vitória/ES – Brasil.
  • Mariana Poltronieri Pacheco Escola Superior de Ciências da Santa Casa de Misericórdia de Vitória – Departamento de Gastroenterologia e Hepatologia – Vitória/ES – Brasil.

Keywords:

Carcinoma, Hepatocellular, Liver Transplantation, Immunotherapy

Abstract

We report the case of a 68-year-old male with alcohol-related cirrhosis, diagnosed with hepatocellular carcinoma (HCC) noteligible for liver transplant. After immunotherapy with atezolizumab associated with bevacizumab, he underwent a successful living donor liver transplantation (LT), not showing disease evidence or graft injury, maintaining clinically and radiologically stable 14 months after surgery. This is a successful report of combined atezolizumab plus bevacizumab being used as a bridge to LT in a patient with HCC, showing an important finding in therapy in patients with unresectable tumors at diagnosis.

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Published

2023-02-11

How to Cite

1.
Solino GA, Ferreira RPC, D’Albuquerque LAC, Farias AQ, Trindade LZ, Vasconcelos VF de, et al. Atezolizumab plus Bevacizumab as a Bridge for Liver Transplant in Hepatocellular Carcinoma. bjt [Internet]. 2023 Feb. 11 [cited 2025 Mar. 31];26. Available from: https://bjt.emnuvens.com.br/revista/article/view/444

Issue

Vol. 26 (2023)

Section

Case Report

License

Copyright (c) 2023 Gabriela Azevedo Solino; Raphael Paiva Cock Paiva Cock Ferreira; Luiz Augusto Carneiro D’Albuquerque, Alberto Queiroz Farias, Lívia Zardo Trindade, Vitor Fiorin de Vasconcelos, Mariana Poltronieri Pacheco

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.