Pancreas Transplant Alone for Non-Uremic Type I Diabetes - Report of the two first Cases on RS

Abstract

This paper aims to report the first two cases of isolated pancreas transplantation in Rio Grande do Sul, Southern Brazil, as well as to discuss its indications and results. Case 1 - Female, 32 years-old, diabetic since 17 years-old, inadequate metabolic control and presenting with chronic diabetic complications. Transplantation was performed on 12 February 2003 at São Lucas Hospital, PUCRS. Case 2 - Female, 29 years-old, diabetic since 14 years-old, unsatisfactory metabolic control and chronic diabetic complications. Transplantation performed on 02 March 2003. Systemic-bladder drainage was used. Quadruple immunosuppression (induction therapy, tacrolimus, MMF and prednisone) was employed. Clinical outcome was good for both patients, with excellent metabolic control achieved at the end of the first year. We conclude that, in selective patients, pancreas transplant alone is an effective option to control complicated type I diabetes.