Analysis of organ transplantation markers and the donation process in the state of Pará

Abstract

The current study aimed to demonstrate adherence to the drugs of the therapeutic immunosuppressant regime in liver transplanted individuals. It was performed an integrative review of the literature in articles published between 2004 to 2014. Data were collected on the Medline, Scielo, Pubmed and BVS databases with the following descriptors: medication compliance, medication adherence, cumplimiento a la medicación, transplante de fígado, liver transplantation and transplante hígado. The search originated 37 articles. After an analytical reading, it resulted 22 complete articles. From the analysis, it emerged 2 categories: Factors related to the non-adherence (NA) and interventions contributing to the adherence. Factors related to NA were psychosocial risks, abuse of substances, poor adherence to the treatment, and decreasing awareness of the Disease in the pre transplant period (Tx). As to the post-Tx period, factors analyzed were male gender and dependent, living alone, young, higher educational level, presence of common side effects, intake of the daily medication, negative beliefs on the medication, the perception of the Tx drugs and medicines. TheInterventions contributors to the accession have been the adjustment of the medication dose reduction in taken by day, and psychological care from the pre-Tx period and pharmaceutical care in the postoperative period. According to this study, it was concluded that the health care teams should assess major aspects of the candidates and to implement effective strategies from the pre-Tx period to the post-Tx follow-up, in order to attain a higher adherence to the immunosuppressive therapy regime in the post-Tx.